Journal article
A longitudinal study of children identifies antibody Fc-mediated functions and antigen targets of immunity to Plasmodium vivax malaria
DH Opi, RJ Longley, E Takashima, T Spelman, Y Tayipto, K Schoffer, J Brewster, L Reiling, BD Wines, B Kiniboro, P Siba, M Harbers, M Hogarth, T Tsuboi, LJ Robinson, I Mueller, JG Beeson
Immunity | Published : 2026
Abstract
Understanding immunity against Plasmodium vivax, a leading cause of malaria, will accelerate development of vaccines, which are currently lagging. Opi et al. identify important mechanisms and target antigens of protective P. vivax immunity in children, including combinations of responses that afford greater protection, revealing pathways for vaccine development.
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Awarded by NIAID NIH HHS